en_tn_condensed/gen/42/38.md

My son will not go down with you

"My son, Benjamin, will not go with you to Egypt"

with you

Here "you" is plural and refers to Jacob's older sons.

For his brother is dead and he alone is left

"For my wife, Rachel, only had two children. Joseph is dead and Benjamin is the only one left"

on the road in which you go

"while you a traveling to Egypt and back" or "while you are away." Here "road" stands for traveling.

then you will bring down my gray hair with sorrow to Sheol

"then you will cause me, an old man, to die of sorrow"