en_tn/1ti/04/05.md

it is sanctified by the word of God and prayer

Here "word of God" and "prayer" are used together to express one idea. The prayer is in agreement with the truth that God has revealed. Alternate translation: "it is dedicated for God's use by praying in agreement with his word" (See: rc://en/ta/man/jit/figs-hendiadys)

it is sanctified

This can be stated in active form. Alternate translation: "we sanctify it" or "we have set it apart" (See: rc://en/ta/man/jit/figs-activepassive)

word of God

Here "word" refers to God's message or what he has revealed. (See: rc://en/ta/man/jit/figs-metonymy)