with the wine of her sexual immorality the inhabitants of the earth became drunk

The wine represents sexual immorality. Alternate translation: "the people of the earth became drunk by drinking her wine, that is, they were sexually immoral" (See: rc://en/ta/man/jit/figs-distinguish and rc://en/ta/man/jit/writing-symlanguage)

her sexual immorality

This may well have a double meaning: sexual immorality among people and also the worship of false gods. (See: rc://en/ta/man/jit/figs-metaphor)