en_tn/isa/01/15.md

I hide my eyes from you

This idiom is a way of saying "I will not look at you" or "I will not pay attention to you" (See: rc://en/ta/man/translate/figs-idiom)

your hands are full of blood

This is the reason that God will not listen to their prayers. The blood likely refers to violence that they have done against people. AT: "because it is like your hands are covered with the blood of those you have harmed" or "because you are guilty of violence" (See: rc://en/ta/man/translate/figs-metonymy)