en_tn_condensed/isa/51/18.md

There is no one ... to guide her; there is no one ... to take her by the hand

These two clauses have the same meaning and can be combined. This speaks of Jerusalem being helpless as if the city were a drunk woman without a son to help her walk safely. Alternate translation: "You have no one to help you! You are like a drunk old woman without a son to take her by the hand and guide her" (See: rc://en/ta/man/translate/figs-parallelism and rc://en/ta/man/translate/figs-metaphor)