# God predestined us for adoption

"God planned long ago to adopt us". The word "us" refers to Paul, the Ephesian church, and all believers in Christ.  

# God predestined us

"God chose us ahead of time" or "God chose us long ago"

# for adoption as sons

Here "adoption" refers to becoming part of God's family. Here the word "sons" refers to males and females. Alternate translation: "to be adopted as his children" 

# through Jesus Christ

God brought believers into his family by the work of Jesus Christ.

# his will

"God's will"