# the leaders among the Jews

These are the Jewish civil or religious leaders present in Rome.

# Brothers

Here this means "Fellow Jews."

# against the people

"against our people" or "against the Jews"

# I was delivered as a prisoner from Jerusalem into the hands of the Romans

"some of the Jews arrested me in Jerusalem and placed me in the custody of the Roman authorities"

# into the hands of the Romans

Here "hands" stands for power or control.