This is a poetic device. It does not mean that a specific number of sins had been committed, but indicates that many sins had led to God's judgment. See how you translated these words in [Amos 1:3](../01/03.md).
Yahweh uses two negatives here to emphasize that he would punish them. See how you translated these words in [Amos 1:3](../01/03.md). (See: [[rc://en/ta/man/jit/figs-litotes]])
The assumed knowledge is that Esau, from whom the people of Edom were descended, was the brother of Jacob, from whom the people of Israel were descended. Here "his brother" represents the people of Israel. Alternate translation: "he pursued the people of Israel" (See: [[rc://en/ta/man/jit/figs-explicit]] and [[rc://en/ta/man/jit/figs-metonymy]])
These two phrases mean the same thing and are repeated to emphasize his continued anger. The abstract nouns "anger" and "wrath" can be translated using the adjectives "angry" and "furious." Alternate translation: "He was continually angry and always furious" (See: [[rc://en/ta/man/jit/figs-parallelism]] and [[rc://en/ta/man/jit/figs-abstractnouns]])