This means that the person is experiencing such pain that he must lie in bed. AT: "with pain so that he must lie in bed" (See: [[rc://en/ta/man/translate/figs-explicit]])
These two phrases mean basically the same thing, that the person is in so much pain that he cannot even eat. The person is represented by his "life" and his "soul." AT: "the result is that he does not desire any food, not even very special food" (See: [[rc://en/ta/man/translate/figs-parallelism]] and [[rc://en/ta/man/translate/figs-synecdoche]])